What is BPC 157 and How Can It Benefit You? Le Jolie Med Spa BPC 157 can be taken orally or subcutaneously, and for most people there is no difference in efficacy.Yes, some people will notice one works better than the other. Yes, some people will claim that BPC 157 is one of the most unique peptides naturally found in the gut and effective both orally and by injection., Oral supports gut health, while the injectable version helps with healing and People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation. The Basics Behind BPC 157 Injections and Their Effectiveness Your Health Magazine