During the prodromal phase of acute radiation sickness, which mechanism causes the symptoms: acute inflammation, direct caustic injury, glutathione depletion, or vascular compromise? Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high fat diet fed obese mice Scientific Reports Figure 1 from Dossier : Oxidative stress pathologies and antioxidants The importance of glutathione in human disease Semantic Scholar Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease