Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Glucose 6 Phosphate Dehydrogenase Deficiency Associated Hemolytic Anemia and Methemoglobinemia in a Patient Treated With Hydrox Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy Glucose 6 Phosphate Dehydrogenase Deficiency Oncohema Key A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway Nature Chemical Biology