SULFORAPHANE ROLE IN AGING AND NEURODEGENERATION Sulforaphane potently activates the Nrf2 pathway, upregulating stress response genes similar to exercise and fasting., Why is this important?, It boosts glutathione, the bodys primary antioxidant, in Mark There are thousands of phytochemicals that upregulate our antioxidant and longevity genesso what makes sulforaphane so special? Sulforaphane upregulates glutathione. Often referred to as the mother of all antioxidants, glutathione Sulforaphane's Multifaceted Potential: From Neuroprotection to Anticancer Action Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation