Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Figure 1 from Oral melanotic macule a case report. Semantic Scholar Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. A Case Report of Oral Malignant Melanoma: A Silent Killer Cureus Oral Mucosal Melanosis IntechOpen