Body copper homeostasis and clinical manifestations in Wilson disease. Download Scientific Diagram What is Wilson disease? It's a rare condition where excess copper builds up in the body, affecting the function of the liver, brain, and other organs. Early signs and symptoms Wilson's disease is a potentially fatal condition that causes copper to build up in various organs. In this test specific episode of the "Answers From the Lab" podcast, Joshua Bornhorst, Ph.D., explains how What is the safe topical dosing, duration, and contraindications for the copperbinding peptide GHKCu for wound healing or antiaging? Hepatolenticular degeneration (Wilson disease) is a genetic disorder caused by impaired copper metabolism, leading to copper accumulation in multiple organsespecially the liver and brain. It typically presents with a combination of: