Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar Melanotan 2. Nasal tan Pharma one Peptides Melanotan 2 Cyclic Heptapeptide for Melanocortin Research Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.