Labial melanotic macules in atopic dermatitis. (a) Multiple macular Download Scientific Diagram Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Labial lentigines, also called labial melanotic macules, is a benign skin condition that is more common in individuals with darker skin. They most often appear during adulthood although they can develop at Labial melanotic macule