aspirin [TUSOM Pharmwiki] Acetaminophen and aspirin toxicity are both high yield, but the injury pattern is very different. Acetaminophen overdose overwhelms glutathione, allowing NAPQI to build up and cause hepatic necrosis. The antidote is N acetylcysteine, which Glutathione peroxidase activity in blood cells from aspirin induced asthma patients The study does not imply that paracetamol causes asthma and some children do need more paracetamol than the rest for the growing respiratory problems Aspirin