File:Glutathion metabolism DE state in G6PD deficiency.png Wikimedia Commons Glucose 6 Phosphate Dehydrogenase Modulates Cytosolic Redox Status and Contractile Phenotype in Adult Cardiomyocytes Circulation Research In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione Glucose 6 Phosphate Dehydrogenase Deficiency (G6PDD) Pathology of G6PD deficiency Pathology Made Simple
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