Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Pathology Outlines Melanoma Pathology Outlines Melanotic macule Pathology Outlines Staging mucosal melanoma of the head & neck This is a very rare case of metastatic oral mucosal melanoma to the colon with an unusual presentation mimicking melanosis coli. The colonoscopy findings show no mass effect but multiple hyperpigmented lesions