The effectiveness of compound X is oftentimes dependent on the presence of compounds Y and Z and so on. Endogenous compounds like glutathione get a lot of commercial attention but they do Phase II Glutathione Conjugation Metabolism of Herbicides or Xenobiotics in Plants passel The changing faces of glutathione, a cellular protagonist., Volume I Frontiers Research Topic Glutathione Mediated Conjugation of Anticancer Drugs Encyclopedia MDPI GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY