GHK Cu vs NAD+: Which Longevity Peptide Should You Take or Stack? Figure 2. [Growth hormone binding to the]. Endotext NCBI Bookshelf Antiinflammatory Action of Glucocorticoids New Mechanisms for Old Drugs New England Journal of Medicine Topically applied GHK as an anti wrinkle peptide: Advantages, problems and prospective How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin