Pigmented Lesions of the Oral Mucosa Pocket Dentistry Can a black pigmented lesion of the oral cavity predict future development of melanoma Report of a case and review of literat Pathology Outlines Melanoma ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Pathology Outlines Mucosal melanoma (genital, oral, sinonasal)