Hypothyroidism (underactive thyroid) is more common in people with Down syndrome. About 40% of the adolescents and adults with Down syndrome we have seen at our clinic have hypothyroidism. One of the Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer Scientific Reports The immune system in Hashimoto's thyroiditis: Updating the current state of knowledge on potential therapies and animal model construction ScienceDirect Glutathione and Autoimmune Disease Master Antioxidant 14 Glutathione Benefits for Your Body and Health Annex Naturopathic Clinic