Melanotan II (Tan Jabs): Why They're Not Worth The Risk Melanotan II is a synthetic peptide developed with the original scientific goal of stimulating the body's natural melanin production. Researchers explored it as a potential way to help protect skin from UV Melanotan 2: Evaluations, investigations, and more George Herald MD breaking down Melanotan II Part 2 of my peptide series. The research, the risks, the reality. Long term safety data? Nonexistent. PDF) Melanotan II reverses autistic features in a maternal immune activation mouse model of autism