Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral Melanotic Macule: Symptoms and Treatment Skinsight Relative frequency of solitary melanocytic lesions of the oral mucosa Buchner 2004 Journal of Oral Pathology & Medicine Wiley Online Library Oral Melanosis