The evidence is clear: Young E cigarette users suffer from respiratory symptoms American Lung Association Frontiers Aerosolized nicotine from e cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection E liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos ScienceDirect E cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme ScienceDirect Electronic Cigarette Aerosol Modulates the Oral Microbiome and Increases Risk of Infection: iScience